DENDRAL was an early expert system, developed initially in the 1960s, that used domain specific knowledge about chemical structure in order to work alongside chemists to create new scientifc results. In some ways this can be seen as a precursor to current scientific discovery systems such as AlphaFold.
Used on page 423
Links:
Encyclopedia Britanica: DENDRAL expert system- doi.org: article: DENDRAL: A case study of the first expert system for scientific hypothesis formation
- Wikipedia: Dendral